There are a number of  ways to restore an imbalance in the nervous system that deals with stress and the body’s ability to adapt to change in the environment, and keep healthy; however, neuromodulation is one of the most effective among them.

Neuromodulation is convenient, suitable for most lifestyles, and devices are portable for use anywhere and anytime.

Clinical studies have shown that vagal stimulation modulates the pain network and immune system. Long-term VNS seems to induce neuromodulatory antinociception through both peripheral and central, ascending and descending pathways.

It is believed to modulate inflammation, oxidative stress, autonomic activity, opioid response, central sensitization, and pain perception.

In addition, VN integrity is critical for antinociceptive effects of opioids. (Yuan and Silberstein, 2016b)