---
title: How does VNS help with chronic pain? | Knowledge Hub | Byond Healthcare
description: Learn more about how vagus nerve stimulation helps with chronic pain on the Byond Healthcare Knowledge Hub.
---

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# How does VNS help with chronic pain?

Chronic pain affects approximately 20% of the general population, and can be divided into nociceptive, neuropathic and nociplastic pain.  Chronic neuropathic pain concerns around 8% of the population **and includes migraine and headache which are a major cause of disability.**

Chronic pain patients generally have inadequate pain relief or disabling side effects using currently available treatments.  Thus, may turn to other therapeutic options, including neurostimulation. 

A device has been developed for the treatment of primary headache disorders by stimulating the cervical branch of the vagus nerve. Studies indicated that nVNS may reduce the pain associated with a migraine attack when the device was used within 20 minutes from pain onset, and reduce the onset frequency of chronic cluster headache ([Moisset etal., 2019](https://pubmed.ncbi.nlm.nih.gov/31637517/)).

In addition to treatment of migraine and cluster headache, VNS has also shown to stimulate the anti-inflammatory pathways in preclinical trials for a wide range of inflammatory conditions, including: sepsis, lung injury, rheumatoid arthritis, diabetes, and fibromyalgia ([Johnsona and Wilson, 2018](https://pubmed.ncbi.nlm.nih.gov/29844694/)).

One of the main potential benefits of tVNS for the treatment of chronic pain and inflammation is that it is a non-invasive and well-tolerated treatment. 

In terms of its effectiveness, tVNS has shown promise as a treatment for chronic pain and inflammation due to the activation of serotonergic and noradrenergic neural systems. This theory is based on reports from patients indicating a decrease in pain sensation ([Johnsona and Wilson, 2018](https://pubmed.ncbi.nlm.nih.gov/29844694/)).

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The Byond Healthcare knowledge hub shares expert content about the vagus nerve and the benefits of vagus nerve stimulation, with a specific focus on non-invasive vagus nerve stimulation, with individuals, healthcare providers and medical representatives.

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