---
title: VNS & Neurological Effects | Knowledge Hub | Byond Healthcare
description: Vagus nerve stimulation has been linked to several regions of the brain and affects different neurotransmitters. Read more.
---

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# What is the link between VNS and neurological effects?

The vagus nerve connections allow it to modulate the function of higher brain centers, forming the basis for its potential use in many disorders. ([Ben-Menachema et al., 2018](https://pubmed.ncbi.nlm.nih.gov/25614179/urgically%20implanted%20and%20non-invasive%20vagus%20nerve%20stimulation:%20a%20review%20of%20efficacy,%20safety%20and%20tolerability.%20Eur%20J%20Neurol.%202015;22(9):1260-1268.%20doi:10.1111/ene.12629))

Vagus nerve stimulation has been linked to several regions of the brain and affects different neurotransmitters [(Yuan and Silberstein, 2016c)](https://pubmed.ncbi.nlm.nih.gov/26364805/). 

**Limbic system**

- Epilepsy, mood, pain and memory

 **Interbrain**

- Satiety, inflammation, epilepsy, pain and autonomic system

**Midbrain**

- Pain, epilepsy, and mood

**Pons**

- Epilepsy, pain, mood, motor skills, sleep, autonomic interoception

**Medulla**

- A major efferent to the gastrointestinal tract, heart and lungs, motor skills, autonomic system, sleep, and chemoreceptors

**Cerebellum**

- Autonomic system

**Spinal cord**

- Pain and the autonomic system

 

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The Byond Healthcare knowledge hub is exists to share expert content about the vagus nerve and the benefits of vagus nerve stimulation, with a specific focus on non-invasive vagus nerve stimulation, with patients, healthcare providers and medical representatives.

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